Voprazan® contains vonoprazan, an active pharmaceutical ingredient belonging to a newer class of gastric acid-suppressing agents known as potassium-competitive acid blockers (P-CABs). This medication is used for the treatment of erosive esophagitis, relief of heartburn associated with gastroesophageal reflux disease (GERD), and treatment of Helicobacter pylori infection.
Generic Name: Vonoprazan
Dosage Forms: 10 mg and 20 mg film-coated tablets
Voprazan® contains vonoprazan, an active pharmaceutical ingredient that suppresses gastric acid secretion through potassium-competitive inhibition of the gastric proton pump. It is indicated for the acute and maintenance treatment of erosive esophagitis, relief of heartburn associated with gastroesophageal reflux disease (GERD), and, in combination with antibiotics, the treatment of Helicobacter pylori infection.
Compared with proton pump inhibitors (PPIs), Voprazan® provides a faster onset of action and more sustained suppression of gastric acid secretion. Vonoprazan achieves its full therapeutic effect from the first day of treatment, often after a single dose. It may be particularly beneficial for patients with severe or recurrent gastroesophageal reflux disease (GERD) who continue to experience symptoms despite treatment with PPIs. Another advantage of Voprazan® is its flexibility of administration, as it can be taken with or without food, offering greater convenience and facilitating treatment adherence.
Take one 10 mg or 20 mg tablet once or twice daily, as prescribed by your physician, with a glass of water, with or without food.
Warnings and Precautions
Pregnancy and Breastfeeding
Inform your physician or pharmacist about all medications you are taking, including prescription and non-prescription drugs, vitamins, and herbal supplements.
Voprazan® may affect the activity of other medicines, and other medicines may affect how Voprazan® works.
Common adverse effects (for erosive esophagitis or heartburn)
Gastritis (stomach inflammation) or stomach pain, dyspepsia, bloating, nausea, diarrhea, constipation, hypertension, and urinary tract infection
Common adverse effects (for H. pylori treatment with antibiotics)
Abdominal pain, temporary taste disturbance, diarrhea, headache, hypertension, vaginal fungal infection, and flu-like symptoms
Do not take more than prescribed. In case of overdose, contact your physician immediately.
For erosive esophagitis or heartburn
Take the missed dose as soon as possible within 12 hours. If more than 12 hours have passed, skip the missed dose and take the next dose at the scheduled time.
For H. pylori treatment
Take the missed dose as soon as possible within 4 hours. If more than 4 hours have passed, skip the missed dose and continue your regular schedule until completion of therapy.
Bottle containing 30 film-coated tablets. Each tablet contains 10 mg or 20 mg of vonoprazan.